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Literature summary extracted from

  • Ohno, Y.; Nara, A.; Nakamichi, S.; Kihara, A.
    Molecular mechanism of the ichthyosis pathology of Chanarin-Dorfman syndrome Stimulation of PNPLA1-catalyzed omega-O-acylceramide production by ABHD5 (2018), J. Dermatol. Sci., 92, 245-253 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.296 a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide Homo sapiens
-
 a diacyl-sn-glycerol + a linoleate-esterified acylceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.296 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.296 HEK-293T cell
-
 Homo sapiens
-
2.3.1.296 HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.296 a linoleate-containing triacyl-sn-glycerol + an ultra-long-chain omega-hydroxyceramide
-
 Homo sapiens a diacyl-sn-glycerol + a linoleate-esterified acylceramide
-
 ?
2.3.1.296 additional information ABHD5 promotes enzyme-dependent acylceramide production by retaining triglycerides in the endoplasmic reticulum and presenting them to the enzyme to promote substrate recognition Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.296 PNPLA1
-
 Homo sapiens